Core Sequences
Core sequences at the UBC MRI Research Centre that are in use in many studies.
3D T1
| Hi Res (0.8 x 0.8 x 0.8 mm3) MPRAGE | |
|---|
| Coil | dSTREAM 32 channel head coil |
| Orientation | Sagittal Oblique |
| FOV (mm) | 256 x 256 x 180 |
| Slice thickness (mm) | 0.8 |
| # of Slices | 225 |
| Matrix | 320 |
| Voxel size F x P x S (mm) | 0.8 x 0.8 x 0.8 |
| TR (ms) | 2400 |
| TE (ms) | 4.3 |
| Inversion Time | 950 |
| Flip angle (deg) | 8 |
| Parallel Imaging Factor | CS = 3.6 |
| Acquisition time | 5:50 |
| 1 x 1 x 1 MPRAGE | |
|---|
| Coil | dSTREAM 32 channel head coil |
| Orientation | Sagittal Oblique |
| FOV (mm) | 256 x 256 x 180 |
| Slice thickness (mm) | 1 |
| # of Slices | 180 |
| Matrix | 256 x 256 |
| Voxel size F x P x S (mm) | 1 x 1 x 1 |
| TR (ms) | 2400 |
| TE (ms) | 3.6 |
| Inversion Time | 950 |
| Flip angle (deg) | 8 |
| Parallel Imaging Factor | CS = 3.6 |
| Acquisition time | 3:42 |
Functional MRI (fMRI)
| VBRAIN Single Echo fMRI | |
|---|
| Coil | dSTREAM 32 channel head coil |
| Orientation | Axial Oblique |
| FOV (mm) | 240 x 240 x 155 |
| Slice thickness (mm) | 2.5 |
| Slice gap (mm) | 0 |
| # of Slices | 62 |
| Matrix | 96 |
| Voxel size F x P x S (mm) | 2.5 x 2.5 x 2.5 |
| TR (ms) | 2000 |
| TE (ms) | 30 |
| Flip angle (deg) | 77 |
| Echos | 1 |
| Parallel Imaging Factor | 2 |
| Multiband Factor | 2 |
| Acquisition time | Task dependent, 8-10min recommended for resting state |
Diffusion Tensor Imaging (DTI)
| DTI Hardi60 b1000 | |
|---|
| Coil | dSTREAM 32 channel head coil |
| Orientation | Axial Oblique |
| FOV (mm) | 224 x 224 x 150 |
| Slice thickness (mm) | 2 |
| Slice gap (mm) | 0 |
| # of Slices | 75 |
| Acquisition matrix | 112 |
| Voxel size F x P x S (mm) | 2 x 2 x 2 |
| Reconstruction matrix | 112 |
| TR (ms) | 3800 |
| TE (ms) | 67 |
| b-values (s/mm2) | 0, 1000 |
| # of directions | 60 |
| # of T2 images | 4 |
| Parallel Imaging Factor | 1 |
| Multiband Factor | 3 |
| Acquisition time | 4:11 |
| Reverse gradient polarity scan | 0:11 |
| Total scan time | 4:21 |
| DTI 98dir | |
|---|
| Coil | dSTREAM 32 channel head coil |
| Orientation | Axial Oblique |
| FOV (mm) | 224 x 224 x 150 |
| Slice thickness (mm) | 2 |
| Slice gap (mm) | 0 |
| # of Slices | 75 |
| Acquisition matrix | 112 |
| Voxel size F x P x S (mm) | 2 x 2 x 2 |
| Reconstruction matrix | 112 |
| TR (ms) | 3900 |
| TE (ms) | 75 |
| b-values (s/mm2) | 0, 500, 1000, 2000 |
| # of directions | 98 |
| # of b=0 (T2) images | 10 |
| Parallel Imaging Factor | 1 |
| Multiband Factor | 3 |
| Acquisition time | 7:07 |
| Reverse gradient polarity scan | 0:11 |
| Total scan time | 7:18 |
| DTI 128dir | |
|---|
| Coil | dSTREAM 32 channel head coil |
| Orientation | Axial Oblique |
| FOV (mm) | 224 x 224 x 150 |
| Slice thickness (mm) | 2 |
| Slice gap (mm) | 0 |
| # of Slices | 75 |
| Acquisition matrix | 112 |
| Voxel size F x P x S (mm) | 2 x 2 x 2 |
| Reconstruction matrix | 112 |
| TR (ms) | 4000 |
| TE (ms) | 79 |
| b-values (s/mm2) | 0, 500, 1000, 2000 |
| # of directions | 128 |
| # of T2 images | 12 |
| Parallel Imaging Factor | 1 |
| Multiband Factor | 3 |
| Acquisition time | 9:26 |
| Reverse gradient polarity scan | 0:13 |
| Total scan time | 9:39 |
Susceptibility Weighted Imagine (SWI) / Quantitative Susceptibility Mapping (QSM)
| SWI | |
|---|
| Coil | dSTREAM 32 channel head coil |
| Orientation | Axial |
| FOV (mm) | 220 x 180 x 170 |
| Acquired slice thickness (mm) | 0.9 |
| Recon slice thickness (mm) | 0.76 |
| # of Slices | 224 |
| Acquired matrix | 244 x 200 |
| Recon matrix | 288 |
| Acquired voxel F x P x S (mm) | 0.9 x 0.9 x 0.9 |
| Recon voxel F x P x S (mm) | 0.76 x 0.76 x 0.76 |
| Bandwidth (Hz) | 180 |
| TR (ms) | 35 |
| TE/Delta TE (ms) | 5.2/6.4 |
| # of echos | 5 |
| Flip angle (deg) | 15 |
| Parallel Imaging Factor | CS = 4.5 |
| Acquisition time | 5:37 |
| Flyback | Yes |
| Flow comp | Yes |
| Reconstructions | SWI Magnitude & SWI Filtered Phase,
QSM Magnitude & Unfiltered Phase of each echo |
| Fast SWI | |
|---|
| Coil | dSTREAM 32 channel head coil |
| Orientation | Axial |
| FOV (mm) | 220 x 180 x 180 |
| Acquired slice thickness (mm) | 0.9 |
| Recon slice thickness (mm) | 0.76 |
| # of Slices | 224 |
| Acquired matrix | 256 x 152 |
| Recon matrix | 288 |
| Acquired voxel F x P x S (mm) | 0.8 x 1.1 x 1.3 |
| Recon voxel F x P x S (mm) | 0.76 x 0.76 x 0.76 |
| Bandwidth (Hz) | 180 |
| TR (ms) | 35 |
| TE/Delta TE (ms) | 5.2/6.4 |
| # of echos | 5 |
| Flip angle (deg) | 15 |
| Parallel Imaging Factor | CS = 6 |
| Acquisition time | 2:26 |
| Flyback | Yes |
| Flow comp | Yes |
MR Spectroscopy (MRS)
| semi-LASER MRS | |
|---|
| Coil | dSTREAM 32 channel or Neurovascular 15 channel head coil |
| Orientation | Study specific |
| Minimum voxel volume (mL) | 6 |
| Minimum shim volume (cm) | 1 in each direction |
| Samples | 2048 |
| Spectral bandwidth | 2000 |
| Sat bands/REST slabs | 0 |
| Centre frequency (ppm) | 2.0 |
| Shifted metabolite display (ppm) | 4.7 |
| # water suppression shots | 64 |
| # non-water suppression shots | 4 |
| Save individual shots | yes (.data/.list and .sdat/.spar files) |
| TR (ms) | 5000 |
| TE (ms) | 33 |
| Flip angle (deg) | 90 |
| Shim | Volume based, 2nd order |
| Water suppression | Philips “Excitation” option with 100Hz window |
| PNS mode | High |
| Gradient mode | Maximum |
| Acquisition time | Approx. 7 min depending on voxel size |
