Introduction
Quantitative Susceptibility Mapping (QSM) is a non-invasive MRI technique that quantifies the underlying magnetic susceptibility distribution of biological tissue1. By quantifying magnetic tissue properties QSM overcomes the limitations of traditional
clinical MRI techniques, such as SWI, R2*, and phase imaging, enabling differentiating between iron and calcium deposits and providing improved sensitivity to myelin variations.
Analysis of QSM
In order to compute susceptibility maps from MRI phase data multiple processing steps have to be performed. Our Matlab QSM toolbox – QSM.m – has efficient implementations of various algorithms for each step in the QSM pipeline including our own RTS dipole inversion method.2 With our toolbox, total QSM reconstructions times of less than 30s are achievable.