3T MRI

Approved Projects on the 3T Philips Scanner

	Study	PI	Department	Year
MRI	OLERO (Roche/MN43964) study -A Multi-center, Single-arm, Open-label, Extension, Rollover Study to Evaluate the Long-term Safety and Efficacy of Ocrelizumab in Patients with Multiple Sclerosis. Study MN43964 (Olero) is a single-arm, open-label extension (OLE), rollover study of ocrelizumab that allows for participants in Parent studies to continue treatment with ocrelizumab and thereby, aims at the continuation of collecting long-term safety and efficacy data.	Robert Carruthers	MS & NMO Clinical Trials Group	2023
MRI, FLAIR, rs-fMRI, DTI	“A Placebo-Controlled Efficacy in iNPH Shunting (PENS) Trial” - Adult Hydrocephalus Study. Idiopathic Normal Pressure Hydrocephalus is a condition of over- accumulation of cerebrospinal fluid (CSF) commonly seen in the elderly and of unknown cause, with current treatment paradigms involving surgical interventions such as shunting the CSF from the ventricles in the brain to the peritoneum in the abdomen. The current literature surrounding INPH has been insufficient and there remains a need for a placebo controlled study. The Placebo-Controlled Effectiveness in INPH Shunting (PENS) trial is a multi-centre blinded, randomized, placebo-controlled design investigation of CSF shunt surgery.	Thomas Zwimpfer	Neurosurgery	2023
MRI, FLAIR, DTI, rs-fMRI, tb-fMRI, Single Echo	Modulating interhemispheric inhibition after stroke. The aim of this work is to identify biomarkers to predict who will respond to interventions involving inhibitory brain stimulation after stroke, and generate new knowledge related to our understanding of the mechanisms of inhibitory brain stimulation. While inhibitory brain stimulation shows promise in promoting recovery after stroke when paired with motor practice, its response is variable: we do not know how stroke-related factors influence its subsequent impact on motor-related brain activity. By employing task-based functional magnetic resonance imaging pre and post stimulation, the current study will examine the impact of inhibitory brain stimulation on motor-related brain activity after stroke.	Lara Boyd	Physical Therapy	2023
MRI, FLAIR, SWI, DWI	UX701-CL301. A Randomized, Double-blind, Placebo-controlled, Multicenter, Seamless, Adaptive, Safety, Dose-finding, and Phase 3 Clinical Study of UX701 AAV-mediated Gene Transfer for the Treatment of Wilson Disease, Industry (Ultragenyx)	Vladimir Marquez Azalgara	Gastroenterology	2022
MRI-PDFF	Merck NASH MK-3655-001. A Phase 2b Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-3655 in Individuals with Pre-cirrhotic Nonalcoholic Steatohepatitis	Saumya Jayakumar	Gastroenterology	2022
MRI, FLAIR, rs-fMRI, DTI, MWI	IMPACT 360 for Healthy Agers. The purpose of this study is to evaluate effects of a multimodal intervention in healthy older adults and elucidate mechanisms driving associated changes. Participants will take part in a 6 month intervention involving exercise, mindfulness, and nutrition. The comprehensive assessment will focus on: cognition, inflammation, microbiome diversity, sleep quality, neurological imaging markers, fitness, cardiovascular health, and well-being. This assessment will: 1) Help us understand the mechanisms behind the benefits of this intervention and any interactive effects and 2) to serve as a normative dataset for replication in clinical populations.	Silke Appel- Cresswell	Neurology	2022
MRI, FLAIR, rs-fMRI, DWI, MWI, SWI	Canadian Longitudinal Study on Aging (CLSA): Follow-up 3, Healthy Brains and Healthy Aging Initiative. The CLSA Healthy Brains, Healthy Aging Initiative is a six-year study, funded by the Weston Family Foundation, that will create new datasets to enhance the CLSA database and facilitate independent research into the link between lifestyle, the human microbiome, and brain health. The study will involve 6,000 research participants enrolled in the CLSA, including more than 2,500 who will undergo magnetic resonance imaging (MRI) to monitor brain structure and function as they age. The resulting standardized datasets will be available for use by approved public-sector researchers in Canada and internationally.	Teresa Liu-Ambrose	Physical Therapy	2022
MRI, FLAIR, DWI, QRM, SWI	Colchicine for the Prevention of Vascular Events after an Acute Intracerebral Hemorrhage (CoVasc-ICH) – Optional MRI Sub-study. CoVasc-ICH Optional MRI Sub-Study enrolls interested participants from the main CoVasc-ICH study. This sub-study will try to determine the effects of colchicine on perihematomal edema formation and remote diffusion weighted imaging lesions on MRI.	Thalia Field	Vancouver Stroke Program	2022
MRI, rs-fMRI, fMRI, MWI, SWI, DTI	Mechanisms of non-invasive brain stimulation as a treatment option for patients with Parkinson's (All-Dressed). In this study, Parkinson’s Disease subjects perform a simple motor task, while they receive subthreshold Electrical Vestibular Stimulation (EVS), and we simultaneously record motor vigour, fMRI and EEG. Different “calibration” stimuli will be delivered in the scanner, and the resultant recordings will be used to train a model to predict vigour from an arbitrary set of stimulation parameters. Precision designed EVS will be later tested outside of the scanner to see if this results in clinically-relevant enhancements in motor task performance.	Martin McKeown	Neurology	2022
MRI, ASL, DWI, DTI, SWI, MWI	(ACQUIRE) Feasibility of multi-domain data acquisition in patients at risk for hypoxic-ischemic brain injury following cardiac arrest: a cohort study. The ACQUIRE study designed to assess the feasibility data collection in multiple domains (Cerebral Blood Flow using transcranial Doppler, biomarkers of neurologic injury, electroencephalography and neuroimaging). In addition, we are seeking to determine the feasibility of clinical outcome assessment and neuroimaging at 6-months.	Don Griesdale (with Will Panenka)	Dept. of Medicine, Anaesthesiology	2022
MRI, FLAIR, ASL, rs-fMRI, DTI, SWI	FCD - Memory after Concussion 2.0. This study aims to advance our understanding of why memory problems often persist after concussion, after the brain has seemingly healed. We will be collecting MRI data to confirm that memory complaints after concussion are not directly related to measures of traumatic brain pathology, including corpus callosum white matter integrity and microbleeds. Using resting state fMRI, we will also investigate functional connectivity between the salience network and memory system in the brain in individuals with memory complaints after concussion and those without such complaints to determine whether differences between groups are observable at the level of brain function.	Noah Silverberg	Psychology	2022
MRI, FLAIR, DTI (MDD), Spectro - single voxel, QRM (MWI)	Prediction of Cognitive and Motor Symptom Progression in Multiple Sclerosis Using Myelin Imaging. A.K.A: Longitudinal Observation of Brain and Spinal cord T2 Relaxation – Brief Interlude Subsequent Quantitative Evaluation (LOBSTR BISQUE). In this study, we will ask our previous volunteers with MS to return 4 years after their original visit so we can collect additional physical, cognitive and myelin MRI data. We will explore whether the amount of myelin at the beginning of the study can predict changes in disability. We will also use new MRI tools to determine what other biological changes, in addition to myelin damage, are linked to progression. Understanding the link between biological changes (in particular myelin) and physical and cognitive changes will allow these more specific imaging methods to be used in clinical trials trying to slow myelin damage and progression.	Shannon Kolind	MS & NMO Clinical Trials Group	2022
MRI, FLAIR Novel optimized ultrashort echo time multiband hydrogen pulse sequences	Radiofrequency Pulse and Pulse Sequence Design for Accelerated Sodium Magnetic Resonance Imaging. While MRI excels at for detailed images of soft tissue lesions, including those due to traumatic brain injury, it difficult to use MRI to characterize damage to the bone. Ultrashort echo time (UTE) pulse sequences enable the acquisition of signal from tissues with short T2 relaxation time, but they overall scan times tend to be very long due to inefficiencies elsewhere in the sequence. This work aims to develop novel, optimized RF pulse sequences by employing novel MB prepulses.	Rebecca Feldman	Physics & Astronomy	2022
MRI	A randomized, open-label, parallel-group, 18-month Phase 3 study to evaluate the effect of venglustat compared with usual standard of care on left ventricular mass index in participants with Fabry disease and left ventricular hypertrophy” Sanofi EFC16158 CARAT.	Anna Lehman	Adult metabolic Diseases Clinic	2022
MRI, 3 PLANE, FLAIR	F. Hoffmann-La Roche - FENTREPID (GN41791) study - - Site 327128. NeuroRx Research. A Phase III Multicenter, Randomized, Double Blind, Double Dummy, Parallel Group Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared with Ocrelizumab in Adult Patients with Primary Progressive Multiple Sclerosis. A study to evaluate the efficacy and safety of fenebrutinib on disability progression in adult participants with Primary Progressive Multiple Sclerosis (PPMS). All eligible participants will be randomly assigned to either daily oral fenebrutinib (or placebo) or intravenous (IV) ocrelizumab (or placebo).	Robert Carruthers	MS & NMO Clinical Trials Group	2022
MRI, 3 PLANE	A randomized, open label, multi-center, active-comparator study to assess the efficacy, safety and tolerability of ofatumumab 20mg sc monthly versus continued current therapy in relapsing-remitting multiple sclerosis after elevation of serum neurofilament light levels (SOSTOS). Novartis This study will evaluate if relapsing-remitting MS patients that have not had a relapse in the past year would benefit from a switch to ofatumumab versus staying on their continued current therapy. This study will also look at whether an elevated serum neurofilament light (NfL) level predicts enhanced benefit from a switch to ofatumumab.	Alice Schabas	MS & NMO Clinical Trials Group	2022
MRI, DTI, ihMT	Advanced MRI techniques to measure spinal cord microstructure in vivo: development and reproducibility.    This study involves testing advanced MRI techniques (myelin water imaging, inhomogeneous magnetization transfer and diffusion imaging) to measure changes in the spinal cord after spinal cord injury. In this first stage we will optimize these techniques for spinal cord scanning on our 3T scanner and determine reproducibility for white and grey matter regions of interest.	Corree Laule	ICORD/ MRI Research Centre	2022
MRI	A Randomized, Double-Blind, Placebo-Controlled Dose Range Finding Study with Open-Label Extension to Evaluate the Safety. Tolerability, Pharmacokinetics and Pharmacodynamics of LMI070/branaplam when Administered as Weekly Oral Doses in Participants with Early Manifest Huntington's Disease.	Blair Leavitt	Centre for Huntington Disease	2022
MRI, DWI, FLAIR,	A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel-group, 76-Week Study Evaluating the Safety and Efficacy of Two Doses of Simufilam in Subjects with Mild-to Moderate Alzheimer’s Disease. This study will investigate the safety and effectiveness of simufilam with those in placebo, in participants who are diagnosed with mild to moderate Alzheimer disease. Simufilam is an oral drug meant to restore the normal shape and function of a brain protein called filamin A (FLNA). In patients with Alzheimer disease, the shape of FLNA is distorted. This triggers toxic signaling beta amyloid, and ultimately results in brain cell degeneration and inflammation.	Robin Hsiung	Neurology	2022
MRI, DWI, DTI, FLAIR, rs-fMRI, ASL	Roche WN42444 study: A Phase III, Multicenter, Randomized, Parallel-Group, Double-Blind, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of Gantenerumab In Participants At Risk For Or At The Earliest Stages Of Alzheimer’s Disease. People who have elevated brain amyloid levels may be at risk for or at the earliest stages of Alzheimer’s disease because they have signs of one of two core pathologies of Alzheimer’s disease (abeta amyloid or herein simply “amyloid”), although they do not have symptoms. The purpose of Study WN42444 is to compare the effects, good or bad, of gantenerumab with those of placebo in participants who are cognitively unimpaired and have elevated levels of amyloid protein in the brain. Gantenerumab is a man-made antibody that attaches to amyloid in the brain and mobilizes the immune system to remove it.	Robin Hsiung	Neurology	2022
MRI, tb-fMRI	Transfer of Valence - fMRI equipment testing. Prior work suggests that emotion not only alters memory for emotional content per se but can also alter memory for and attitudes towards associated experiences, a process known as transfer of valence. The neural correlates of these effects, however, have yet to be thoroughly investigated. To help us gain a better understanding of how emotion affects transfer of valence, we will ask participants to study pairs of images: one object (always neutral) and one scene (negative or neutral). We will then have participants complete a test phase where they will rate the pleasantness of the neutral objects followed by a memory task to determine memory for the pairings in each condition (negative vs. neutral).	Daniela Palombo	Psychology	2022
3-point Dixon; Proton spectroscopy	Sexual dimorphism in physiological and bioenergetic responses to aerobic exercise. Physical activity is a necessity for healthy living and dependent on the delivery of oxygen to the working muscles to generate energy. Our understanding of the body’s response to physical activity has primarily been characterized using the “typical 70-kg man”, yet substantial sex-differences in the lungs, heart, blood vessels, blood, and muscle may lead men and women to use different mechanisms to deliver oxygen and produce energy during activity. Our study will investigate these differences with a focus on various muscle characteristics including quantity, structure, fibre type, and respiratory capacity.	Robert Boushel	Kinesiology/ Fac. Of Education	2022
MRI, DTI, rs-fMRI	Left intermittent Theta Burst Stimulation vs. Right Low Frequency Repetitive Transcranial Magnetic Stimulation Effectiveness in Depression and Suicidal Ideation: A Randomized Non-Inferiority Trial (Left vs. Right Non-Inferiority Trial - LeRNIT). MDD poses a great economic burden on the health care system due to its long-term disability with a low ability to participate in everyday activities. We aim to understand the mechanism of action of rTMS in clinical practice, improve the targeting of this treatment avenue using functional MRI scans, and investigate novel markers, such as heart rate variability, as an indication of treatment response. https://ninet.med.ubc.ca/research/	Fidel Vila-Rodriguez	Psychiatry	2021
MRI, MWF, FLAIR	VISIONARY-MS: A Phase 2, Randomized, Double-Blind, Parallel Group, Placebo Controlled Study for the Treatment of Visual Pathway Deficits In Chronic Optic Neuropathy to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of CNM-Au8 For Remyelination In Stable Relapsing Multiple Sclerosis (RMS). CLENE Nanomedicine, SNAC-Sydney Neuroimaging Analysis Centre.	Tony Traboulsee	MS & NMO Clinical Trials Group	2021
MRI, DWI, STIR	Evaluation the role of transcervical 3D Ultrasound imaging of the oropharynx during transoral robotic surgery - TORS. Transoral robotic surgery has the potential to provide better surgery outcome to patients with early-stage oropharyngeal SCC, and advances in image guidance during this procedure can optimize resection margins, as well as reduce the risk of complications such as neurovascular injury. The objective of our study is to assess the utility of using 3D transcervical ultrasound to assess oropharyngeal anatomy and pathology and the feasibility of ultrasound-MRI registration for intraoperative image guidance.	Eitan Prisman & Tim Salcudean	Surgery + Electrical & Computer Engineering	2021
MRI, rs-fMRI, tb-fMRI	Functional role of eye movements during motor sequence learning (Short title: Sensorimotor imaging & learning [SMiLE]). The sensorimotor imaging & learning (SMiLE) study will evaluate how oculomotor control contributes to implicit motor sequence learning in healthy, young and older adults. Participants will practice a novel skilled reaching task for 3 days and undergo structural and functional magnetic resonance imaging before and after training. We will investigate change in brain connectivity associated with motor sequence learning. Our findings will contribute to better understanding of the underlying mechanisms contributing to skill learning in healthy adults.	Lara Boyd	Physical Therapy	2021
MRI, rs-fMRI	Technical development time to test new MR-Rapid open bird-cage MR coil for concurrent TMS-MRI applications in phantoms	Fidel Vila-Rodriguez	Psychiatry	2021
MRI, DWI, FLAIR	LIBERTO- Single arm, open label multicenter extension study to evaluate the effectiveness and safety of Ocrelizumab in patients with multiple sclerosis previously enrolled in a F. Hoffmann-La Roche sponsored Ocrelizumab phase IIIb/IV clinical trial.	Robert Carruthers	MS & NMO Clinical Trials Group	2021
MRI, tb-fMRI	Emotional Localization. We want to investigate how emotional distractions around us can influence how we see and interact with other non-emotional objects arounds us. Specifically, we want to understand information presented to different senses (e.g., vision, audition) impacts our spatial awareness of the environment. We will utilize specialized behavioral tasks and powerful MRI scanners to help us uncover the underlying patterns of brain activity that guides our attention and action when we are emotionally stimulated.	Rebecca Todd	Psychology	2021
MRI, rs-fMRI, fMRI	Adapt and Avoid – fMRI. Altered patterns of avoidance behaviours – which entail taking or withholding action to prevent unpleasant outcomes – are a feature of anxiety and depression; however, we only have a limited understanding of the neural circuits that underpin these behaviours. To address this gap in the literature, we adapt an rodent-based investigation of the neural correlates of avoidance behaviours into a human context (in which participants must learn which stimuli are associated with the need to make or withhold a series of button presses in order to avoid an unpleasant outcome). In particular, we focus on the neural representations of stimuli that signal the appropriate avoidance response to be made and the aversive or neutral outcome of the response to these stimuli.	Rebecca Todd	Psychology	2021
MRI, rs-fMRI, tb-fMRI	Cannabis and Polysubstance Use: Imaging Response Inhibition and Stress Exposure (CAPU RISE). Most stimulant users also use cannabis. The majority of cannabis users report stress reduction and coping motives for their use; however, there remains little biological evidence of cannabis reducing acute stress. This randomized control clinical drug trial employs a range of methods including biosampling, self-reports, actigraphy, and neuroimaging to examine the effects of cannabinoids on stress response, inhibition, and sleep in cannabis and stimulant co-users.	Christian Schütz	Psychiatry	2021
MRE, MRI-PDFF	The Sonic Incytes Liver Incyte System, evaluation of liver fibrosis and steatosis versus MRE and MRI PDFF. SI-CLIN-02. This study aims to evaluate the correlation of liver elasticity measurements between an investigational ultrasound-based measurement device (Liver Incyte System, manufactured by Sonic Incytes), the standard of care (FibroScan) as well as the non-invasive gold standard (MRE). In addition, this project aims to evaluate the discriminatory ability and investigate cut-offs for different stages of liver disease progression of the Liver Incytes System.	Alnoor Ramji	Gastroenterology, GI Research Institute	2021
MRE, MRI-PDFF	A Phase 2b Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-3655 in Individuals With Pre-cirrhotic Nonalcoholic Steatohepatitis (Merck NASH).	Alnoor Ramji	Gastroenterology, GI Research Institute	2021
MRI, rs-fMRI, fMRI	Individualized pathways to recovery after stroke. Pairing brain stimulation with rehabilitation after stroke is a promising approach. However, early studies of this intervention responses proved to be highly variable. Some people showed a strong benefit while others did not. The main aim of the proposed program of research is to identify biomarkers that can be used to predict response to brain stimulation interventions. www.brain.rehab.med.ubc.ca	Lara Boyd	Physical Therapy	2021
MRI, MRS,	MRS in healthy participants: Neurochemical Atlas. This study involves creating a metabolic map of the cingulate gyrus using optimized MRS parameters (sLASER, TR/TE=5000/32ms). We will examine the link between each voxel’s glutamate concentration and pain sensitivity (i.e., pain thresholds and laser evoked potentials). Further, the spatial distribution and variability of all metabolic concentrations will be examined.	John Kramer, Erin MacMillan	ICORD	2021
MRI, rs-fMRI	Technical proposal for testing real-time motion detection/ correction patch	Fidel Vila-Rodriguez, Erin MacMillan	Non-Invasive Neurostimulation Therapies Lab (NINET) / MRI Research Centre	2021
MRI, rs-fMFI, DTI, QRM (MWI)	A prospective and longitudinal investigation of concussive and subconcussive mild traumatic brain injury mechanisms in ice hockey. This study aims to address the public health problem of concussions and subconcussive head impacts in contact sports such as ice hockey. Our investigation will examine the mechanisms of (sub)concussions on brain function changes with mechanical trauma occurred over multiple hockey seasons. Findings from the study will inform how accumulation of trauma leads to long-term health problems including depression and severe personality change.	Alex Rauscher, Lyndia Wu	MRI Research Centre, Mechanical Engineering	2021
MRI, DWI, SWI, MWI, rs-fMRI	Canadian Longitudinal Study on Aging: Coronavirus Disease 2019 (CLSA: COVID) Study. Canadian Longitudinal Study on Aging COVID-19 Study: This study will compare brain structure, connectivity, and risk of silent stroke in older persons who have a history or symptoms of COVID-19 compared to older people without a history or symptoms of COVID-19.	Teresa Liu-Ambrose	Physical Therapy, Canada Research Chair in Physical Activity, Mobility, and Cognitive Health	2021
MRI, DWI, ASL	"ANAVEX2- 73", A Phase 2b/3, Double-Blind, Randomized, Placebo-Controlled 48-week Safety and Efficacy trial of ANAVEX2-73 for the Treatment of Early Alzheimer’s Disease (AD). This study will investigate the safety and effectiveness of ANAVEX2-73 in people diagnosed with early to mild Alzheimer disease. Participants will be randomised to receive either high or low dose ANAVEX2-73 or placebo (33% chance) over a period of 48 weeks. The study drug may protect brain neurons (brain nerve cells) that are usually damaged in Alzheimer’s disease, which may enable ANAVEX2-73 to modify AD. After the screening and baseline visit, participants will return to the Clinic every 3 months for assessments that include cognitive testing, sleep questionnaires, study partner interviews, occasional safety labs, urinalysis and ECG. Outcome measures include regular assessments of cognitive and functional abilities.	Robin Hsiung	Neurology	2021
MRI, DWI, QRMs	"EMBARK", Phase 3b Open-Label, Multicenter, Safety Study of BIIB037(aducanumab) in Subjects with Alzheimer’s disease Who Had Previously Participated in the Aducanumab Studies 221AD103, 221AD301, 221AD302 and 221AD205. The Biogen EMBARK study is an open-label, longitudinal study of the investigational drug aducanumab. The aim of the study is to assess the long-term safety and efficacy of monthly infusions of aducanumab in patients with Alzheimer disease. The study includes magnetic resonance imaging (MRI), positron emission tomography (PET), electrocardiography (ECG), blood sampling, cerebral spinal fluid (CSF) sampling (optional), neuropsychological testing, and caregiver interviews to assess the effects and safety profile of aducanumab.	Robin Hsiung	Neurology	2020
MRI, DTI, SWI, ASL, Perfusion	TRIC-VSI. Trial of Remote Ischemic Conditioning in Vascular Cognitive Impairment. People with mild vascular cognitive impairment are prone to having little strokes, which can cause changes in cognition over time. Currently there are no treatments for mild vascular cognitive impairment that are approved by Health Canada. This study investigates whether Remote Ischemic Conditioning (cutting off blood flow to a limb temporarily without causing tissue damage) can be implemented successfully by patients, and whether it will improve cognition, brain imaging and blood markers.	Thalia Field	Neurology	2020
MRI, rs-fMRI, tb-fMRI	Modulating interhemispheric inhibition after stroke. The aim of this work is to identify biomarkers to predict who will respond to interventions involving inhibitory brain stimulation after stroke, and generate new knowledge related to our understanding of the mechanisms of inhibitory brain stimulation. While inhibitory brain stimulation shows promise in promoting recovery after stroke when paired with motor practice, its response is variable: we do not know how stroke-related factors influence its subsequent impact on motor-related brain activity. By employing task-based functional magnetic resonance imaging pre and post stimulation, the current study will examine the impact of inhibitory brain stimulation on motor-related brain activity after stroke.	Lara Boyd / Sarah Kraeutner	Physical Therapy	2020
MRS	MRS Multisite B0 Drift Phantom Study. Contribution of phantom MRS data to a multisite B0 drift study lead by researchers at Johns Hopkins University.	Erin MacMillan	MRI Research Centre	2020
MRI, DWI, QRM, MT	Natural History of Mild Degenerative Cervical Myelopathy: an observational study. This study will permit identification of the key clinical, radiological and serum biomarker related variables predicting clinical deterioration of degenerative cervical myelopathy (DCM) patients. Such knowledge will facilitate improvements in the treatment of DCM, allowing surgeons to provide personalized recommendations depending on expected clinical course.	Nicolas Dea	ICORD, Neurosurgery	2020
MRI, SWI	CANARY- Clinical dAta, Natural language pRocessing and eYe tracking for dementia risk stratification. Our study is attempting to explore the relationship that exists between eye movement patterns, speech patterns, and cognitive decline. This study compares the speech and eye-movements of people with Alzheimer’s disease (AD) and mild cognitive impairment (MCI) to healthy volunteers, to see if there are patterns that can be used to detect Alzheimer’s disease early, and to monitor the progression of Alzheimer’s disease over time. Link to our study: https://www.vchri.ca/research-study/clinical-data-and-natural-language-processing-early-detection-dementia-canary	Thalia Field	Neurology	2020
MRI, rs-fMRI	Burnout and Resilience among Medical Professionals during COVID-19. Burnout in the medical field has long been recognized as a significant problem. Currently available strategies to reduce burnout and build resilience against it are of limited effectiveness and are highly variable in their outcomes. This research will inform the selection and further development of more effective strategies, by using functional magnetic resonance imaging (fMRI) to provide a strong neuroscientific basis for the selection process. UBC Cognitive Neuroscience of Thought Laboratory: http://www.christofflab.ca/	Kalina Christoff	Centre for Brain Health	2020
MRE	A Phase 2, randomized, double-blind, placebo-controlled, multicenter, multinational, dose-finding study to evaluate the efficacy and safety of CC-90001 compared with placebo, in subjects with non-alcoholic steatohepatitis (NASH) and Stage 3 or Stage 4 liver fibrosis.	Eric Yoshida	Gastroenterology	2020
rs-fMRI, Perfusion, MRI	ALLFTD: ARTFL-LEFFTDS Longitudinal Fronto-temporal Lobar Degeneration. The study aims to evaluate sporadic (s-) and familial (f-) frontotemporal lobar degeneration (FTLD) patients and asymptomatic family members of f-FTLD patients, characterizing the cohorts longitudinally and informing clinical trial design. The study has two arms: a “longitudinal arm” involving a comprehensive assessment of clinical, functional, imaging, and biofluid data collection, and a “biofluid-focused arm” involving limited clinical data to accompany biospecimen collection.	Ian Mackenzie	Pathology & Laboratory Medicine	2020
DWI, FLAIR, SWI	CATIS-ICAD, Combination Antithrombotic Treatment for prevention of recurrent Ischemic Stroke in IntraCranial Atherosclerotic Disease: Protocol for a Pilot randomized trial.	Samuel Yip	Vancouver Stroke Program	2020
MRI	FH Achilles Tendon Longitudinal (FHATL) Study. Our study aims to enhance our understanding of the impact of Familial Hypdercholesterolemia on tendon health; a highly under-researched area of significant clinical importance. With the use of non-invasive techniques, we aim to examine various determinants of tendon functional recovery in individuals with newly diagnosed Familial Hypdercholesterolemia. This information is fundamental in identifying if current Familial Hypdercholesterolemia treatments methods reverse the functional and structural effect of the lipid accumulation within the tendon.	Alexander Scott	Centre for Hip Health & Mobility	2020
MRI, fMRI , BOLD,	Neural Recruitment During Spontaneous Thoughts. People frequently experience thoughts which seem to ‘come out of nowhere’, however, the neural underpinnings of this common psychological happening are poorly understood. Using fMRI scanning, we will investigate neural activity in human brains before a thought reaches one’s awareness, once it reaches awareness, during its subsequent elaboration (as a stream of thought), and during its dissipation. Find out more about this research on our laboratory website: http://www.christofflab.ca/	Kalina Christoff	Psychology	2020
MRI, SWI, FLAIR	Myelin Water Imaging in NMDA Receptor Autoimmune Encephalitis – Pilot Study. Autoimmune encephalitis (AIE) is a serious condition caused by misdirected immune response against the brain. Magnetic Resonance Imaging (MRI) is used for the detection of brain abnormalities in many neurological conditions but routine MRI studies are normal in the majority of AIE cases, despite the obvious widespread neurological dysfunction. We aim to determine if there is damage to myelin due to widespread inflammation using Myelin Water Imaging (MWI) in AIE patients and if these relate to abnormalities in cognitive testing, serum neurofilament light-chain levels (a blood biomarker of neuronal damage), and retinal measurements obtained by optical coherence tomography.	Tony Traboulsee	MS & NMO Clinical Trials Group	2020
MRI, fMRI, DTI	CAN-BIND Validation study- Intergrated Biological Markers for the Prediction of Treatment Response in Depression. The purpose of our study is to learn about ‘biomarkers’ (biological features such as proteins, genes, and brain images that indicate the state of a disease in a person), and how they can help predict treatment outcomes in patients with clinical depression. This study involves standard treatment for depression. Patients will be treated by a psychiatrist for 16 weeks with an antidepressant medication approved to treat depression. No placebos are being used.	Raymond Lam	Psychiatry	2020
MRI	SEARCH - StrokE and vAscular Risk factors contributing to neuroCognitive decline in adult congenital Heart disease. Adults with Congenital Heart Disease (ACHD) are at increased risk of clinical and silent infarcts as well as dementia. The SEARCH study will be the first prospective cohort study in ACHD patients evaluating silent cerebrovascular disease over time, and how this is associated with cognitive changes and other vascular risk factors. We will evaluate 400 ACHD patients in BC over 3 years using neuroimaging, cognitive testing, and other imaging and bloodwork to try to address these knowledge gaps.	Thalia Field	Neurology	2020
MRI-PDFF, MRE	A Phase 3, Multinational, Double-Blind, Randomized, Placebo-Controlled Study of MGL-3196 (resmetirom) in Patients With Non-Alcoholic Steatohepatitis (NASH) and Fibrosis to Resolve NASH and Reduce Progression to Cirrhosis and/or Hepatic Decompensation- Madrigal MG-3196-11.	Eric Yoshida	Gastroenterology	2019
MRI, MRI-PDFF	The Sonic Incytes Liver Incyte System, assessment of liver fibrosis and steatosis, SI-CLIN-01. This study looks to compare the use and results of a new ultrasound based measurement device (Liver Incyte, manufactured by Sonic Incytes) to the standard of care (FibroScan) as well as the non-invasive gold standard (MRE). In addition we would like to compare the fat measurement ability of ultrasound attenuation coefficient compared to that of MRI-PDFF.	Eric Yoshida	Gastroenterology	2019
MRI	Long-term extension safety and efficacy study of SAR442168 in participants with relapsing Multiple Sclerosis	Tony Traboulsee	MS & NMO Clinical Trials Group	2019
MRI	The Longitudinal Course of Intracortical Myelination and Cognitive Function in Bipolar Disorder	Lakshmi Yatham	Psychiatry	2019
MRI, rs-fMRI, MRSI	Offsetting hippocampal degeneration in moderate to severe TBI. This randomized control trial is assessing the feasibility and efficacy of an online 16-week intervention employing allocentric spatial navigation tasks to enhance learning and memory capacity and to improve structure and function of the hippocampus following a moderate-severe traumatic brain injury (m-sTBI). Participants will undergo an MR scan, blood collection, and an assessment of behavioural outcomes 7 months and 12 months following a m-sTBI. Participants in the treatment arm complete the online intervention between these time-points while the controls do not.	William Panenka	Psychiatry	2019
MRI, tb-fMRI, MWF	Cortical Responses to Visual Triggers in Urgency Urinary Incontinence Demonstrated Through Functional Magnetic Resonance Imaging.	Lynn Stothers	ICORD	2019
rs-fMRI	Regional brain activation during different forms of response inhibition, comparing young healthy adults with individuals with Bipolar Disorder. People living with bipolar disorder often have problems with controlling impulsivity. Using MRI, we will identify subcomponents of response inhibition, a specific form of impulsivity. After, participants will receive 3 rounds of Transcranial Magnetic Stimulation (TMS) to test whether or not we can use it to change impulsivity.	Christian Schütz	Psychiatry	2019
MRI, rs-fMRI	The GBA multimodal study	Jon Stoessl	Neurology, Pacific Parkinson Research Centre	2019
MRI, MEDIC	Hemorrhage within the spinal cord after acute traumatic injury - the relationship to hemodynamic management and thromboembolic prophylaxis.	Brian Kwon	Orthopaedics, ICORD	2019
MRI	Linking biomechanical and imaging outcomes to better understand the effects of running on knee joint health. Running is a very popular activity for many adults. However, a diagnosis of knee osteoarthritis is often seen as a “death sentence” for someone’s recreational running career. This study will provide the first evidence to determine the safety of runners for people with degenerative cartilage due to osteoarthritis. https://mablab.rehab.med.ubc.ca/currentstudies/	Michael Hunt	Physical Therapy	2019
MRI, DWI	AXIOMATIC - A Global, Phase 2, Randomized, Double-Blind, Placebo- Controlled, Response-Adaptive Dose-Ranging Study of BMS-986177, an Oral Factor XIa Inhibitor, for the Prevention of New Ischemic Stroke or New Covert Brain Infarction in Patients Receiving Aspirin and Clopidogrel Following Acute Ischemic Stroke or Transient Ischemic Attack (TIA)	Philip Teal/ Thalia Field	Neurology	2019
MRI, rs-fMRI, DTI, GRASE	Does Opera training sculpt the brain to learn? Study 1- Language Intensive. Learning how to perform opera is both cognitively and physically demanding, yet some of the students who have been most successful in UBC’s Opera Program have had learning-related disabilities, and appear to have overcome their difficulties, or to have learned compensatory skills that help them not just in opera performance but beyond. The goal of the proposed research is to systematically evaluate and better explain the neural foundations of that observation. In this endeavor, a study is proposed to measure executive function and other learning capabilities before and after a month-long language intensive course that is a required component of UBC opera training, and to determine – through MRI measurement of anatomical changes in fiber tracts in the brain – the neural bases of any observed behavioral improvements.	Lara Boyd	Physical Therapy	2019
MRI, DWI, SWI	CanProCo – Canadian Proactive Cohort Study for People Living with Multiple Sclerosis. Canadian Proactive Cohort Study for People Living with Multiple Sclerosis (CanProCo) is an observational study designed to better understand the factors that contribute to MS disease progression using tools from different fields such as epidemiology (i.e. number of patients and distribution of diseases), medical imaging, and immunology (blood). Subjects will participate in annual visits over a 5-year period.	Tony Traboulsee	MS & NMO Clinical Trials Group	2019
MRI	A Phase 2B Dose-finding study for SAR442168, A Bruton's tyrosine kinase inhibitor, in participants with relapsing Multiple Sclerosis (Sanofi DRI15928)	Tony Traboulsee	MS & NMO Clinical Trials Group	2019
MRI	An open-label, single-arm 4-year study to evaluate effectiveness and safety of Ocrelizumab treatment in patients with Progressive multiple sclerosis. (Roche Consonance- MN39159)	Robert Carruthers	MS & NMO Clinical Trials Group	2019
MRI, MWI	[Roche] Pilot study of PET (Positron Emission Tomography) Imaging: Correlations with Advanced MRI in MS	Robert Carruthers	MS & NMO Clinical Trials Group	2019
MRI	HOPE- Hip Osteoarthritis Progression Evaluation . Population-Based Longitudinal Cohort Study of Femoroacetabular Impingement of the Hip Using Magnetic Resonance Imaging Outcomes. The goals of the study are to investigate whether radiographic FAI and physical activity are risk factors for progression of cartilage damage and other MRI outcomes over 7 years. This study includes a randomly selected population of young adults aged 20-49 with and without hip pain.	Jolanda Cibere	Rheumatology	2019
MRI, DWI	AbbVie. A Phase 2 Multiple Dose, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABBV-8E12 in Subjects with Early Alzheimer´s Disease. This is a 96-week Phase 2 clinical trial for people with mild cognitive impairment to mild Alzheimer disease. The study treatment, an anti-Tau agent, may be able to block soluble tau aggregates, and thereby decrease the spreading of tau pathology in brains with tauopathy. Patients who meet all of the inclusion criteria will receive monthly IV study treatment or placebo for the duration of their enrollment.	Ging-Yuek Robin Hsiung	Neurology	2018
MRI, DTI, rs-fMRI	Multi-Site, Prospective, Longitudinal, Cohort Study Measuring Cerebrospinal Fluid Mutant Huntington Protein in Patients with Huntington’s Disease.	Blair Leavitt	Medical Genetics; Centre for Huntington Disease	2018
fMRI	A randomized, double-blinded, sham-controlled cross-over with open-label extension study of theta-burst stimulation transcranial magnetic stimulation in non-fluent/agrammatic variant primary progressive aphasia.	Fidel Vila-Rodriguez	Psychiatry	2018
MRI, DWI, Elastography	Optimizing the management of high-risk and unfavorable intermediate-risk disease: the use of advanced imaging, trans-perineal mapping biopsies, and dual-strength brachytherapy sources to minimize radiation dose to normal tissues [OPTiMAL]	Michael Peacock	BC Cancer Agency	2018
MRI	PET Studies of dopamine turnover and release in bipolar disorder: Montreal Imaging Stress task PET study	Lakshmi Yatham	Psychiatry	2018
MRI, MTR	MAGNIFY: A 2-year Prospective Study to Evaluate the Onset of Action of Mavenclad® in Subjects with Highly Active Relapsing Multiple Sclerosis	Robert Carruthers	MS & NMO Clinical Trials Group	2018
TMS-fMRI	TMS-fMRI - Treatment response in TRD with interleaved TMS-fMRI	Fidel Vila-Rodriguez	Psychiatry	2018
MRI, MWI	Technical development on the Ingenia Elition: MWI, QSM and FLAIR2	Shannon Kolind, Alex Rauscher, Adam Dvorak	MRI	2018
MRI; SWI; rs-fMRI	HELP_MS; LEMCOG Healthy Controls - A prospective 24-month investigator sponsored trial to determine the course of cognitive function and how it relates to MRI measures of structural and functional connectivity in healthy controls across time. Collection of non-Multiple Sclerosis (MS) untreated control data is invaluable for interpretation of data acquired in MS treatment trials on cognitive outcomes such as memory. Advanced MRI techniques detect differences in the brain between people with and without MS. Understanding differences in brain connection patterns in people without MS helps us to understand the biological changes that may lead to cognitive challenges in MS.	Shannon Kolind	Neurology	2018
MRI; SWI	SMOOTH OPERATOR: Smooth Pursuit as a predictor of cerebral small vessel disease. Cerebral small vessel disease (cSVD) is one of the most prevalent neurological disorders and can lead to problems such as dementia or stroke. However, cSVD is usually only discovered on neuroimaging after symptoms develop. We hope to explore the utility of basic bedside assessments (smooth pursuit eye movements and spontaneous speech patterns) as indicators of the presence and severity of underlying cSVD in pre-symptomatic patients.	Thalia Field	Neurology	2018
MRI; fMRI	ADNI 3: Alzheimer's Disease neuroimaging initiative 3	Ging-Yuek Robin Hsiung	Neurology	2018
MRI, fMRI, DWI	SIGNAL: A Phase 2, multi-center, randomized, double-blind, placebo controlled study in subjects with late prodromal and early manifest Huntington’s disease (HD) to assess the safety, tolerability, pharmacokinetics, and efficacy of VX15/2503.	Lynn Raymond	Centre for Huntington Disease	2018
MRI, fMRI, DWI	Aerobic exercise and CogniTIVe functioning in women with breAsT cancer: the ACTIVATE trial. This study examines the impact of an aerobic exercise intervention on chemotherapy-related cognitive changes (CRCC) in women diagnosed with breast cancer who undergo chemotherapy treatment. The results of this study aim to address the effect and timing of aerobic exercise on CRCC, as well as the outcome of exercise during or following treatment on global measures of brain structure, functioning, and organization through fMRI and EEG assessments.	Kristin Campbell	Physical Therapy	2018
MRI, DTI, SWI	Mapping the medial forebrain bundle in chronic post-concussive syndrome. We propose that injury to the medial forebrain bundle is the cause of the chronic post-concussive syndrome (PCS). This is a proof of concept study involving a single subject with PCS following a rotational head injury.	Trevor Hurwitz with Josue Avecillas- Chasin	Psychiatry	2018
MRI, rs-fMRI, DTI, SWI, DBSI, spectrosc.	Susac Syndrome Advanced Characterization (SuSAC): A Multidisciplinary Assessment of the Disease including Advanced MRI, Ocular Coherence Tomography, and Neuropsychological Testing. Susac Syndrome, a rare autoimmune disease often misdiagnosed as Multiple Sclerosis, and is a poorly understood disease with no proven treatments. This study will be the first to combine a multidisciplinary evaluation of clinical status and disease activity with advanced imaging metrics. The results will provide pilot data that may broaden our understanding of disease pathogenesis and allow important structural and functional relationships to emerge.	Robert Carruthers	MS & NMO Clinical Trials Group	2018
MRI, rs-fMRI, DTI	FOXY- Phase 2 Clinical Trial of Intranasal Oxytocin for Frontotemporal Dementia - MRI Research Centre. The purpose of this study is to evaluate the efficacy of intranasal oxytocin in reducing social apathy in participants with a diagnosis of Fronto-temporal dementia.	Robin Hsiung	Neurology	2018
MRI, Perfusion, Diffusion	When are blood vessels “ready to rupture”? Cerebrovascular health following spinal cord injury. This study explores the cerebrovascular consequences of intermediate (i.e., 1-2 years) and chronic (i.e., >5 years) exposure to daily autonomic dysreflexia in humans with spinal cord injury. We are interested in finding out if the episodic hypertension associated with autonomic dysreflexia impacts cerebrovascular regulation, which plays a role in predisposing this population to cerebral small vessel disease, overt stroke and cognitive decline.	Dr. Andrei Krassioukov	ICORD	2017
fMRI	Scene construction in spontaneous thought. This study will look at the neural basis of the thought dynamics and contents; specifically, the difference between freely moving and deliberately constrained thought, both with and without imagery of spatially anchored scenes. To investigate this, we will combine fMRI and experience sampling.	Dr. Kalina Christoff (w/ Yvette Graveline)	Psychology	2017
MRI, rs-fMRI	Next steps for understanding the neuro-cognitive basis of physical activity adherence. The current study will examine whether individual differences in neural activation using two fMRI experiments predicts future adherence to physical activity over a 6-month period among adults. The first experiment will examine neural responses to the engagement in inhibitory control. The second experiment will examine neural responses to observing health promotion messages related to physical activity and sedentary behavior.	Teresa Liu-Ambrose	Physical Therapy	2017
rs-fMRI; MRI; DTI; SWI	Novel Retinal Biomarkers for Alzheimer's Disease. Detecting the beginning of Alzheimer disease (AD) in the eye by using a noninvasive imaging device that can show amyloid in the retina. This study is an observational, non-treatment study to identify retinal biomarkers associated with AD, and the outcomes measures include 3T MRI, PiB-PET, 3D/2D Retinal Images, Retinal functional tests, and a variety of cognitive and behavioural interviews. The study will assess the efficacy of the device in rodent models and patients with AD, and if successful, the device may lead to better and earlier diagnosis of AD with lower cost.	Robin Hsiung / Prof. Mirza Faisal Beg (SFU)	Neurology	2017
MRI	ENSEMBLE: An Open-Label, Single-Arm Study to Evaluate the Effectiveness and Safety of Ocrelizumab in Patients with Early Stage Relapsing Remitting Multiple Sclerosis	Robert Carruthers	MS & NMO Clinical Trials Group	2017
MRI; rs-fMRI	An Open-Label Extension Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ISIS 443139 in Huntington’s Disease Patients Who Participated in Prior Investigational Studies of ISIS 443139. ISIS 443139-CS2.	Blair Leavitt	Medical Genetics; Centre for Huntington Disease	2017
MRI; rs-fMRI	Reshaping the Path of Mild Cognitive Impairment by Refining Exercise Prescription. In this proposed study, we will study the effects of different types and combinations of exercise training on cognitive function in older adults who are at increased risk for dementia (i.e., mild cognitive impairment). Older adults with mild cognitive impairment represent an ideal target population for intervention strategies, as the preservation of their cognitive function will likely maintain and prolong their ability to live independently and with quality. Furthermore, we will explore how each exercise type improves cognitive function as such information may lead to new discoveries and therapies.	Teresa Liu-Ambrose	Physical Therapy	2017
fMRI	Thought Dynamics (Spontaneous Thought). This study will look at the neural basis of the dynamics of thought; particularly, the differences between freely-moving thought and constrained thought. To investigate this, we will combine experience sampling with fMRI.	Kalina Christoff	Psychology	2017
MRI	Synchronizing Exercises, Remedies in Gait and Cognition (SYNERGIC) Trial. A Randomized Controlled Double Blind Trial. Physical exercises, cognitive training, and vitamin D are low cost interventions and have the potential to enhance cognitive and mobility function in older adults, especially in pre-dementia states such as Mild Cognitive Impairment (MCI). Currently, it is unclear whether aerobic, resistance, or tone and stretching exercise would have different effects on cognitive performance. We postulate that combined strength and aerobic training will have a better effect on cognition over tone stretching-control exercise in an MCI population. Additionally, we will assess if a multi-domain intervention including cognitive training and vitamin D will have synergistic efficacy.	Teresa Liu-Ambrose	Physical Therapy	2017
MRI	Prostate evaluation for clinically important: MRI vs. standard evaluation procedures (PRECISE).	Peter Black (Silvia Chang)	Prostate Centre	2017
MRI	Development of Magnetic Resonance Elastography System for Liver Imaging	Tim Salcudean	Electrical and Computer Engineering	2017
MRI	Testing Inhomogeneous Magnetization Transfer (TIHMT). Inhomogeneous Magnetization Transfer (ihMT) is a new imaging technique that shows promise for myelin selectivity, which could lead to better detection and treatment of demyelinating diseases such as Multiple Sclerosis. This study will compare ihMT to myelin water fraction images, and assess the two techniques’ selectivity to myelin.	Alex MacKay	Physics & Astronomy	2017
MRS	Implementing GABA editing MRS capacity at UBC	Fidel Vila-Rodriguez	Psychiatry	2017
MRI, MRS	MEDDAY- effect of MD1003 in progressive Multiple Sclerosis: A randomized double blind placebo controlled study	Virginia Devonshire	Neurology	2017
MRI; rs-fMRI	LEM-COG: A Prospective 24-Month Observational Study to Evaluate Neurocognitive Function and Safety in Patients with Relapsing Multiple Sclerosis Who Are Initiating LEMTRADA® Treatment in Routine Clinical Practice	Anthony Traboulsee	Neurology	2017
MRI	LOBSTr: establishing an imaging biomarker for disease progression in multiple sclerosis. MS is a disabling neurological disease with a highly variable clinical course including acute disability (relapses when symptoms appear or worsen) and disease progression (steady accumulation of disability in the absence of relapses). There is currently no approved treatment for progressive MS. A principal pathology of MS is the destruction of myelin, which surrounds nerves to speed up signal conduction. We have developed a magnetic resonance imaging technique that provides quantitative measurements of myelin. Our aim is to establish myelin water imaging as a biomarker for disease progression, allowing efficient clinical trials to establish effective treatment options for progressive MS.	Shannon Kolind	Neurology	2017
MRI	COMB ofatumumab versus teriflunomide in patients with relapsing MS	Robert Carruthers	MS & NMO Clinical Trials Group	2017
MRI	MRI Actuator Evaluation/Liver MRE in Healthy Volunteers	Tim Salcudean	Electrical and Computer Engineering	2017
MRI	Subject-specific Mastication Modeling and its applications in Reconstructive Surgery	Sidney FELS (Amir Abdi)	Electrical and Computer Engineering	2017
MRI	Parotid functional mapping using chemical exchange saturation transfer (CEST)	Nevin McVicar / Steven Thomas	Medical Physics	2017
fMRI	EXML – Effect of aerobic exercise on neuroplasticity and motor learning post stroke	Lara Boyd	Physical Therapy	2017
MRS	Glutamate as a biomarker of pain intensity in the anterior cingulate cortex	John Kramer / Corree Laule	Blussal Spinal Cord Centre / ICORD	2017
MRI	The effects of running on knee cartilage measures in people with and without knee osteoarthritis. A pilot study	Michael Hunt	Physical Therapy	2017
MRI	Pilot Study of PET Imaging: Correlation with Advanced MRI inMS	Robert Carruthers	Neurology	2017
MRI	Advanced MRI measures of normal appearing white matter in progressive solitary sclerosis compared to primary progressive MS, relapsing-remitting MS, and healthy controls	Robert Carruthers / Shannon Kolind	Neurology	2017
MRI	Pilot Study for Myelin Water Imaging in Cervical Spinal Cord	Shannon Kolind	Neurology	2016
MRI	Biomarker Study to Explore Mechanism of Action of Ocrelizumab and B-cell Biology in MS (OBOE Study)	Robert Carruthers	MS & NMO Clinical Trials Group	2016
fMRI	MRI of Cerebrovascular Reactivity	Alex Rauscher	Paediatrics	2016
fMRI	Canadian rTMS Treatment and Biomarker Network in Depression (CARTBIND) Trial	Fidel Vila-Rodriguez	Psychiatry	2016
fMRI	Magnetic Resonance Imaging Biomarkers in Amyotrophic Lateral Sclerosis	Sanjay Kalra and Hannah Briemberg	Neurology	2016
fMRI	Randomized double-blind sham-controlled trial of repetitive transcranial magnetic stimulation (rTMS) for bipolar depression	Lakshmi Yatham	Psychiatry	2016
MRI	Phase III, multicentre, randomized, double-blind, placebo-controlled, parallel-Group, efficacy, and safety study of Crenezumab in patients with prodromal to mild Alzheimer's disease (ABBY 3 Study)	Ging-Yuek Robin Hsiung	Neurology	2016
MRI	Detection of metastatic brain tumours using dynamic glucose enhanced MRI after D-Glucose injection	Nevin McVicar	BCCA	2016
MRI	Advanced Quantitative Imaging in Cervical Spinal Cord	Shannon Kolind	Neurology	2016
fMRI	A Medium Chain Triglyceride INTervention for Alzheimer Disease (A MINT for AD) Phase I Study (MINT-01)	Haakon Nygaard	Neurology	2016
fMRI	Canadian Consortium for Neurodegeneration in Aging (CCNA): The Comprehensive Assessment of Neurodegeneration and Dementia (COMPASS-ND) Study	Ging-Yuek Robin Hsiung	Neurology	2016
fMRI	The SARTAN-AD Trial: A randomized, open label, proof of concept study of Telmisartan vs. Perindopril in hypertensive mild-moderate Alzheimer's disease patients	Ging-Yuek Robin Hsiung	Neurology	2016
fMRI	The ENGAGE Study: A Phase 3 Multicenter, Randomized, Double-Blind, Placebo Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Aducanumab (BIIB037) in Subjects with Early Alzheimer's Disease	Ging-Yuek Robin Hsiung	Neurology	2016
fMRI	A novel approach to studying postural instability in Parkinson's disease using functional Magnetic Resonance Imaging (fMRI)	Mark Carpenter	Kinesiology	2016
MRI	Importance of diffusely abnormal white matter on disability and progession in MS	Cornelia Laule	Radiology	2016
MRI	VACCINE Study	Tony Traboulsee	MS Clinical Research	2015
fMRI	Neurobiological Correlates of TMS in NHP	Doris Doudet	Neurology	2015
MRI	ARPEGGIO Study	Robert Carruthers	MS Clinical Research	2015
fMRI	Arrowsmith and mTBI	Naznin Virji-Babul	Physical Therapy	2015
MRI	TOPAZ extension study	Tony Traboulsee	MS Clinical Research	2015
MRI	Mild traumatic brain injury genotyping and phenotyping with advanced imaging, Electroencephalography, and cognitive probes (MTBI)	William Panenka	Psychiatry	2015
MRI	Reshaping the Path of Vascular Cognitive Impairment with Resistance Training	Teresa Liu-Ambrose	Physical Therapy	2015
fMRI	Yohimbine Aging and Reproducibility Study	Doris Doudet	Neurology	2015
fMRI	The Integrated Neurostimulation Platform for Neuropsychiatric Research Group - Investigating predictors of treatment response in treatment-resistant depression (TRD) with interleaved TMS/fMRI	Fidel Vila-Rodrigues	Psychiatry	2015
MRI	The AMARANTH Study: A 24-month, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Efficacy, Safety, Tolerability, Biomarker, and Pharmacokinetic Study of AZD3293 in Early Alzheimer's Disease	Gin-Yuek Robin Hsiung	Neurology	2015
fMRI	Identifying the Neurocognitive Impairments Associated with Recurrent Falling Among Community-Dwelling Seniors	Teresa Liu-Ambrose	Physical Therapy	2015
fMRI	Improving physical activity using an online monitoring tool: a new model of care for knee osteoarthritis	Teresa Liu-Ambrose	Physical Therapy	2015
fMRI	The Effect of Fit Brains Training on Cognitive Performance in Older Adults	Teresa Liu-Ambrose	Physical Therapy	2015
MRI	A Double-masked, Placebo-controlled Study with Open-label Period to Evaluate the Efficacy and Safety of MEDI-551 in Adult Subjects with Neuromyelitis Optica and Neuromyelitis Optica Spectrum Disorders	Robert Carruthers	Neurology	2015
MRI	Relationship between cervical spinal cord microstructure, metabolite concentrations, and neuropathic pain after spinal cord injury	John Kramer	ICORD	2015
MRI	ISIS 443139-CSI	Blair Leavitt	Medical Genetics	2015
MRI	FYN Study: A Phase 2a Multi-Center Study of 18F-FDG PET, Safety and Tolerability of AZD0530 in Mild Alzheimer's disease	Haakon Nygaard	Clinic for Alzheimer disease and Related Disorders	2015
fMRI	Assessment of “normal appearing” white matter in Parkinson's Disease and its association with cognitive dysfunction	Alex MacKay	UBC MRI Research Centre	2015
MRI	Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS)	Ian Mackenzie	Pathology	2015
MRI	Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)	Ian Mackenzie	Pathology	2015
fMRI	Treating Depression in Parkinson's Disease with Transcranial Direct Current Stimulation	Jon Stoessl	Neurology	2015
fMRI	Black Box Theatre of the Mind	Polly Gibbons/Ron Burnett	Emily Carr University	2015
fMRI	Neurological Networks Underlying Cognition in Psychosis	Todd Woodward	Psychiatry	2015
fMRI	Brain Network Interactions	Kalina Christoff	Brain Research Centre	2015
MRI	Comparison of Aripiprazole vs Risperidone on Brain Morphology using MRI - The CARB study	Alasdair Barr	Psychiatry	2015
MRI	Feasibility Study of MR Imaging on Parotid Gland Stimulation (SPIT)	Stefan Reinsberg	Physics	2015
MRI	Tau and Neuroinflammation Imaging in Parkinson's disease and Related Disorders	Jon Stoessl	Neurology	2015
fMRI	Motor Planning Post-Stroke	Lara Boyd	Physical Therapy	2015
MRI	Post Mortem Fetal MRI	Alex Rauscher/Denise Pugash	Paediatrics	2015
MRI	Imaging Tau Accumulation with PBBH3 in Healthy Controls	Jon Stoessl	Neurology	2014
fMRI	Neural corelates of autonomic regulation in elite athletes combining heart rate viariability with fMRI	Lara Boyd	Physical Therapy	2014
fMRI	charactering the impact of silent lesions on stroke recovery using mulimodal neuroimaging	Lara Boyd	Physical Therapy	2014
MRI	Feasibility of spectroscopy and DTI in non-human primates: Pilot study for CIHR	Doris Doudet	Pacific Parkinson's Research Centre	2014
fMRI	Arrowsmith Brain Imaging	Lara Boyd	Physical Therapy	2014
MRI	The Neural Correlates of delusions of reference and recovery from delusions	Mahesh Menon	Psychiatry	2014
MRI	Efficacy of B11B019, Declizumab High Yield Process (DAC-HYP), Monotherapy in subjects with re: An Investigator-Initiated, Multicentre, Phase IV, Open-Label Study to evaluate the biological basis for susceptibility or resistance to disease progression in relapsing-remitting multiple sclerosis patients treated in routine practice with Gilenya for 5 years (IGLOO)	Tony Traboulsee	MS Clinical Research	2014
fMRI	Structural and Functional Correlates of Neuroplastic Change Associated with Stroke	Lara Boyd	Physical Therapy	2014
MRI	What is the relationship between hip musculature; knee joint alignment, pain and function in people with and without knee osteoarthritis?	Karim Khan	Centre for Hip Health and Mobility	2014
fMRI	Sensorimotor plasticity underlying the recovery of skilled walking in people with chronic incomplete SCI	Tania Tam & Lara Boyd	Physical Therapy	2014
fMRI	Characterizing the impact of silent lesions on stroke recovery using multimodal neuroimaging	Lara Boyd	Physical Therapy	2014
MRI	Acoustic Noise Measurement o Noise from single-Shot EPI	Stefan Reinsberg	Physics & Astronomy	2014
fMRI	Structural and Functional Correlates of Neuroplastic Change Associated with Stroke	Lara Boyd	Physical Therapy	2014
MRI	What is the relationship between hip musculature; knee joint alignment, pain and function in people with and without knee osteoarthritis?	Karim Khan	Family Practice	2014
MRI	A randomized controlled study of conventional versus theta-burst repetitive transcranial magnetic stimulation in the treatment of major depressive disorder	Fidel Vila-Rodriguez	Psychiatry	2014
MRE	Magnetic Resonance Elastography of the liver	Tim Salcudean	Electrical Engineering	2014
MRI	Comparative study 0.5T MR Open versus 3.0T MRI - Region of interest: knee	David Hart	Centre for Hip Health and Mobility	2014
MRI	Development of new MRI Techniques for Neuroimaging	Alex Rauscher	Radiology	2014
MRI	Medical Imaging Trial Network of Canada (MINTEC) Protocol C6: Amyloid and glucose PET Imaging in Alzheimer and Vascular Cognitive Impairment patients with significant White Matter Disease	Ging-Yuek Robin Hsiung	Neurology	2014
MRI	The Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease Study - A4	Ging-Yuek Robin Hsiung	Neurology	2014
MRI	A multi-centre, randomized, double-blind, placebo-controlled, phase 3 study to evaluate the efficacy and safety of SA237 as monotherapy in patients with neuromyelitis optica (NMO) and neuromyelitis optica spectrum disorder (NMOSD) Chugai Pharmaceuticals Protocol #: SA-309JG	Tony Traboulsee	MS Clinical Trials	2014
fMRI	Characterizing the Functional Contribution of White Matter Systems within Distributed Neural Networks	Ryan D'Arcy	SFU	2014
MRI	Phase I/II Interventional Clinical Trial of Balloon Venoplasty for Chronic Cerebrospinal Venous Insufficiency in Multiple Sclerosis (CCSVI)	Tony Traboulsee	Neurology	2013
MRS	In Vivo 31P-MR spectroscopy for evaluation of mutation load in a family with MELAS (Mitochontrail Myopathy Encephalopathy, Lactic Acidosis and Stroke like episodes	Gabriella Horvath	Adult Metabolic Diseases Clinic	2013
MRI	A phase-II randomized, double blind, parallel group, placebo-controlled, multi-centre study to evaluate the safety and efficacy of Abatacept in adults with relapsing-remitting Multiple Sclerosis	Joel Oger	Neurology	2013
fMRI	Sensorimotor plasticity underlying the recovery of skilled walkin in people with chronic incomplete spinal cord injury	Tania Lam/Lara Boyd	Physical Therapy	2013
fMRI	PBR28 in healthy controls: serotonergic innervation and Levodopa-derived Dopamine release in PD: an in vivo PET study	Vesna Sossi	Pacific Parkinson's Reasearch Centre	2013
fMRI	Exercise in Parkinson's Disease	Jon Stoessl	Pacific Parkinson's Reasearch Centre	2013
MRI	Myelin Maps ofr T1 and T2 Weighted Scans?	Alex Rauscher	Radiology	2013
fMRI	Neural Basis of Spontneous Thought	Kalina Christoff	Brain Research Centre	2013
fMRI	Regional Brain Activiation during different forms of response inhibition comparing young health adults with problem stimulant users and problem gambers	Christian Schutz	Psychiatry	2013
MRI	Cortical inhibition in unipolar and bipolar depression compared to healthy subjects: a TMS-EEG study	Lakshmi Yatham	Psychiatry	2013
MRE	FTPC: Focal Therapy for Prostate Cancer: A study using focal low dose rate brachytherapy as an alternative to active surveillance and radical treatment forfavourabe risk prostate cancer	James Morris	BC Cancer Agency	2013
MRI	Comparative study 0.5T Open MR vs 3.0T MRI: Region of interest - Knee	David Hart	Centre for Hip Health and Mobility	2013
MRI	Characterization of Dementia due to Mixed Alzheimer and subcortical vascular pathology	Robin Hsiung	Neurology	2013
fMRI	Is there a homunculus in the visual cortex?	Jason Barton	Ophthalmology	2013
MRI	Serial comparisons of abdominal and neurological MRI scans of patients with refractory pychosis disorders (SCAN MRI)	Alasdair Barr	Psychiatry	2013
MRI	DIAN-TU-001: a phase II/III randomized, double-blind, placebo-controled multi-centre study of 2 potential disease modifying therapies in individuals at risk for and with dominantly inherited Alzheimer's disease	Robin Hsiung	Neurology	2013
MRI	T2 relaxometry MRI for the diagnosis of prostate cancer	Piotr Kozlowski	UBC MRI Research Centre	2013
MRI	Development of a new imaging technique of knee cartilage in osteoarthritis	Alex Rauscher	Radiology	2013
fMRI	Exercise-induced and music-induced brain connectivity changes in Parkinson's Disease	Martin McKeown	Neurology	2013
MRI	Tractography after bilateral anterior capsulotomy	Andrew Howard	Psychiatry	2013
fMRI	Neural correlates of autonomic regulation in elite athletes combining heart rate variability with fMRI	Lara Boyd	Physical Therapy	2013
MRI	TRACK-ON	Blair Leavitt	Neurology	2012
MRI	Complications of Parkinson's Disease: The Dopamnergic Basis of Depression; Study 1	Jon Stoessl	Neurology	2012
MRI	IMPAKT-Hip: Natural History of FAI Study	Jolanda Cibere	Orthopaedics	2012
fMRI	Effects of Exposure to Air Pollution on Congitive Function (EAPOC)	Christopher Carlsten	Respiratory Medicine	2012
fMRI	Assessment of Cerebrovascular function using MRI and Blood Gas Manipulation	William Sheel	Human Kinetics	2012
MRI	Study of Myelination in Multiple Sclerosis using MRI and MEPs	Tony Traboulsee	Neurology	2012
MRI	Pseudo-atrophy of the brain in Multiple Sclerosis (Extension)	Tony Traboulsee	Neurology	2012
fMRI	Cognitive characterization of Individuals Genetically At-Risk for Frontotemporal Dementia	Claudia Jacova	Neurology	2012
MRI	MITIGATE-HD	Blair Leavitt	Neurology	2012
FfMRI	Integrated biological markers for the prediction of treatment response in depression	Raymond Lam	Psychiatry	2012
MRI	A Phase II, multicentre, randomized, parallel-group, partially blinded, placebo and Avonex controlled dose finding study to evaluate the efficacy as measured by brain MRI lesions, and safety oftwo does regimens of ocrelizumab in patients with relapsing-remitting multiple sclerosis ROCHE WA21493C/CAT4422g	Lorne Kastrukoff	Neurology	2012
MRI	A PET study of NE Transporter Occupancy and Symptom Response in Depressed Patients Treated with Quetiapine XR	Lakshmi Yatham	Neurology	2012
fMRI	Clinical and neural funcitoning outcomes following group-based family cognitive-behaviour therapy in pediatric obsessive-compulsive disorder (OCD)	Evelyn Stewart	Paediatrics	2012
MRI	The Relationship Between Serotonergic Innervation and Levodopa-Derived Dopamine Release in Parkinson's disease: an in vivo PET Study	Jon Stoessl	Neurology	2012
MRI	Advanced MRI Measures of Repair in Ocrelizumab treated Patients	Tony Traboulsee	Neurology	2012
rs-fMRI	Effects of Brain Magnesium concentration on 31P-MRS and resting state fMRI in ParkinsonÕs disease	Martin McKeown	Neurology	2012
fMRI	Brain Activation during Motor Tasks after SCI	Janice Eng	Physical Therapy	2012
fMRI	Cortical and Subcortical Effects of Galvanic Vestibular Stimulation in Parkinson's Disease	Martin McKeown	Neurology	2012
MRI	Anatomical and functional MRI Correlates of Cognitive Dysfunction in Multiple Sclerosis	Alex MacKay	Physics & Astronomy	2012
fMRI	Neural and Biochemical Correlates of Inner Time Consciousness in Professional Swimmers	Georg Northoff	Psychiatry	2012
MRI	The Evolution of Parkinson's Disease	Jon Stoessl	Neurology	2012
MRS	A Longitudinal Comparison of Aripiprazole vs. Higher Metabolic Risk Antipsychotic Drugs on Adiposity Using MRI (CALM study)	Alasdair Barr	Psychiatry	2012
fMRI	Can exercise improve cancer associated cognitive dysfunction	Kristin Campbell	Physical Therapy	2011
MRI	A multi-centre, randomized, double-blind, placebo-controlled, parallel-group, phase II trial to investigate the efficacy and safety of weekly intra-articular (i.a.) injections of 10, 30, and 100 _g of AS902330 for three consecutive weeks in patients with acute cartilage injury of the knee	David Li	Radiology	2011
MRI	Baminercept: A Multicentre, Randomized, Blinded, Placebo-Controlled, Dose-Escalation Study to Evaluate the Penetration and Pharmacodynamic Effects of Baminercept in the CSF and Safety in Subjects with Secondary Progressive Multiple Sclerosis	Tony Traboulsee	Neurology	2011
MRI	Controlled High Risk Avonex Multiple Sclerosis Prevention Study in Ongoing Neurological Surveillance: CHAMPIONS Continuation Study	Tony Traboulsee	Neurology	2011
MRI	Interhemispheric contributions to neuroplasticity and motor learning after stroke	Lara Boyd	Rehabilitation Sciences	2011
fMRI	A double-blind, randomized, placebo-controlled, parallel-group Phase II study to explore the potential beneficial effects of safinamide on cognition in non-demented patients with idiopathic Parkinson's disease (PD) and cognitive impairment. #EMR 701165-024	Joseph Tsui	Neurology	2011
MRI/fMRI	Neuroimaging in concussion	Alex Rauscher	Radiology	2011
fMRI	Multi-object processing in the ventral stream	Jason Barton	Ophthalmology	2011
fMRI	NeuroDevNet substudy on Fetal Alcohol Spectrum Disorder	Christian Beaulieu	Biomedical Engineering, U of A	2011
MRI	Preparation for advanced imaging at high field: Correlates in formalin fixed brain and spinal cord	Cornelia Laule/Wayne Moore	Pathology & Laboratory Medicine	2011
MRI	Neuroimaging in high altitude climbers	Alex Rauscher	Radiology	2011
fMRI	The effects of nabilone on cue-triggered neural response: Exploring treatment options for cannabis abuse	Elton Ngan	Psychiatry	2011
MRI	Duration of changes in intracortical excitability and cerebral diffusion after transient ischemic attack	Lara Boyd	Rehabilitation Sciences	2011
MRI	A long-term follow-up study of oral ELND005 (AZD-103) in subjects with Alzheimer's Disease	Robin Hsiung	Neurology	2011
MRI	Alzheimer's Disease neuroimaging initiative 2 (ADNI 2)	Ging-Yuek Robin Hsiung	Neurology	2011
MRI	Concussion in youth ice hockey: New frontiers in diagnostic imaging	Naznin Virji-Babul	Physical Therapy	2011
fMRI	The contribution of face parts to face processing	Jason Barton	Ophthalmology	2011
fMRI	Metacognitive Monitoring of Attention	Kalina Christoff	Brain Research Centre	2011
MRI	In Vivo 3-D hip kinematics based on MR Images from patients with femoro-acetabular impingement	Antony Hodgson	Orthopaedic Engineering	2011
MRI	A Phase III, multicentre, randomized, parallel-group, double-blinded, placebo controlled study to evaluate theefficacy and safety of Ocrelizumab in adults with primary progressive Multiple Sclerosis	Tony Traboulsee	Neurology	2011
fMRI	Multimodal functional neuroimaging of the networks underlying cognitive impairment in schizophremia	Todd Woodward	Psychiatry	2011
MRI	Magnetic Resonance Elastography of paitents with prostate cancer	Tim Salcudean	Electrical Computer Engineering	2011
MRI	Psychosis, Exercise and Hippocampal Plasticity	Donna Lang	Psychiatry	2011
MRS	A double-blind, double-dummy, parallel-group study to evaluate the efficacy and safety of Ocrelizumab in comparison to Interferon Beta-1a (Rebif) in patients with Relapsing Multiple Sclerosis ROCHE WA21093/A	Tony Traboulsee	Neurology	2011
MRI	DASB Pilot Study	Jon Stoessl	Neurology	2011
MRS	A Multi-centre, randomized, double-blind, placebo-controlled, study of the efficacy of Natalizumab on reducing disability progression in subjects with secondary progressive Multiple Sclerosis	Virgina Devonshire	Neurology	2011
fMRI	White Matter reorganization in response to motor skill training	Lara Boyd	Physical Therapy	2011
MRI	Compartmentalization of the human neck muscles sternocleidomastoid and splenius capitis	Jean-Sebastien Blouin	Human Kinetics	2010
MRI	TEVA Mega Study - Remyelination in MS with Glatiramer Acetate: Insights from Myelin Water imaging and evoked potentials	Alex MacKay	Physics & Astronomy	2010
MRI	Three-dimensional measurement of knee kinematics in vivo: applications to knee pain and osteoarthritis - in vivo studies, validation b	Dave Wilson	Orthopaedic Engineering	2010
fMRI	Integration of cognitive control and motivational information	Kalina Christoff	Brain Research Centre	2010
MRI	Specialized anatomy of baleen whales	Robert Shadwick	Department of Zoology	2010
fMRI	Expression versus identity processing n the core and extended face networks	Jason Barton	Ophthalmology	2010
fMRI	Role of exercise on cognition and function in seniors with vascular cognitive impairment	Lara Boyd	Physical Therapy	2010
MRI	T1 mapping by 3D T1FFE with variable flip angles for dGEMRIC	Dave Wilson	Orthopaedic Engineering	2010
MRS	A Double-Blind, Placebo-Controlled Study of the safety and Efficacy of ONO-4641 in patients with relapsing Remitting Multiple Sclerosis.	Tony Traboulsee	MS Clinical Research	2010
fMRI	Is there a homunculus in the fusiform gyrus?	Jason Barton	Ophthalmology	2010
fMRI	Functional Connectivity in Motion-Sensitive Visual Cortex	Kalina Christoff/Debbie Giaschi	BRC/Ophthalmology	2010
MRI	Fetal Alcohol Disorders: Gene-environment interactions, predictive biomarkers, and the relationship between structural alterations in the brain and functional outcomes	Christian Beaulieu	University of Alberta	2010
fMRI	Cerebellar Influences in ParkinsonÕs Disease	Martin McKeown	Neurology	2010
MRI	Relationship beween myelin water fraction and electrophysiology of normal white matter within the corpus callosum and the corticospinal tract	Alex MacKay	Physics & Astronomy	2010
MRI	Development of MRE system for prostate cancer imaging	Tim Salcudean	Electrical Computer Eng	2010
fMRI	NSDHL mutations, cholesterol metabolism and working memory: neural underpinnings	Todd Woodward/Cornelius Boerkoel	Psychiatry	2010
MRI	Alzheimer's disease neuroimaging protocol - Grand Opportunity (ADNI-GO)	Robin Hsiung	Neurology	2010
MRI	The Role of CCSVI in Multiple Sclerosis	Tony Traboulsee	Neurology	2010
fMRI	Neural networks involved in working memory in Schizophrenia	Woodward	Psychiatry	2010
MRI	Effects of atypical antipsychotics on metabolism, adiposity and weight gain in children and adolescents	Alasdair Barr	Psychiatry	2010
MRI	A dose blinded extension study to the CBAF312A2201 study to evaluate long-term safety, tolerability and efficacy of BAF312 given orally once dialy in patients with relapsing multiple sclerosis CBAF312A2201E1 Novartis	Joel Oger	Neurology	2010
MRI	DECIDE: a phase 3 multicentre, double-blind, randomized, parallel-group, monotherapy, active-control study to determine the efficacy and safety of Daclizumab High Yield Process (DAC HYP) versus Avonex (Iinterferon_-1a) in patients with relapsing-remitting multiple sclerosis Protocol #: 205MS301 Biogen Idec	Tony Traboulsee	Neurology	2010
MRI	ELND002: a phase 1b, dose-escalating, randomized, placebo-controlled, double-blinded study to evaluate the safety and efficacy of subcutaneous ELND002 in patients with relapsing forms of Multiple Sclerosis Protocol # ELND002-MS103 Elan Pharmaceuticals Inc	Tony Traboulsee	Neurology	2010
MRI	Hepatobiliary imaging in potential living liver donors: Application of high field strength MRI and Primovist contrast agent.	Audrey Spielmann	Radiology	2010
fMRI	Functional Magnetic Resonance Imaging (fMRI) cortical responses in women with overactive bladder before and after pelvic floor therapy.	Lynn Stothers	Urologic Sciences	2010
MRI	Use of Magnetic Resonance venography to characterize Multiple Sclerosis and other white matter pathologies	Alex Rauscher/Tony Traboulsee	UBC MRI Research Centre	2009
MRI	Assessment of hydration effects on MRI measures of spinal cord volume	Roger Tam/Tony Traboulsee	MS/MRI Research Group	2009
MRI	Project to develop a surgical probe for left atrial appendage occlusion surgeries	Jonathan Nakane	Engineering Physics	2009
MRI	Development and validation of a new model of Parkinson's Disease	Doris Doudet	Neurology	2009
MRS	In vivo phosphorus magnetic resonance spectroscopy of the muscle in two siblings with unexplained muscle weakness	Sylvia Stockler-Ipsiroglu	Biochemical Diseases Clinic, BCCH	2009
fMRI	Visual and verfbal problem solving	Kalina Christoff	Brain Research Centre	2009
fMRI	Enhancing cognitive vitality and functional independence in older adults with mild cognitive impairment: A randomized trial of aerobic vs. resistance training	Teresa Ambrose, Todd Handy	Centre for Hip Health	2009
fMRI	Identifying the neurocognitive impairments associated with recurrent falling among community-dwelling seniors	Teresa Ambrose, Todd Handy	Centre for Hip Health	2009
fMRI	Role of supplementary motor rea in motor imagery and motor function in idndividuals with Parkinson Disease	Lara Boyd	School of rehab sciences	2009
fMRI	doing two things at once: how does age influence tasks which challenge both mobility and cognition?	Lara Boyd	School of rehab sciences	2009
MRS	Novartis Pharmaceuticals Canada Inc. Protocol #CBAF312A2201	Joel Oger	Neurology	2009
MRI	Kinematics and muscle activation of the cervical spine during vehicle rollover accidents	Peter Cripton	Orthopaedic Engineering	2009
fMRI	Cortical-STN functional connectivity in Parkinson's disease	Martin McKeown	Neurology	2009
fMRI	Inspiratory Muscke Trainingto Improve Respiratory and |neural function in Peoplewith Stroke	Lara Boyd	School of rehab sciences	2009
fMRI	Controlling Nicotine Craving through down-Regulation of the Insular Cortex	Kalina Christoff	Brain Research Centre	2009
MRI	Genzyme Substudy	Tony Traboulsee	MS Clinical Research	2009
MRS	Roche Genetech study WA21493/ACT4422g	Tony Traboulsee	MS Clinical Research	2009
MRS	Minocycline (CIS)	Tony Traboulsee	MS Clinical Research	2009
fMRI	Real-Time Experience Sampling	Kalina Christoff	Brain Research Centre	2009
fMRI	Studies on Music Processing in Persons with Alzheimer Disease	Ging-Yuek Robin Hsiung	Neurology	2009
MRI	PREDICT-HD v.2.0	Lynn Raymond	Neurological Sciences	2009
MRI	IMAX Study: Maximal simultaneous boost: A dose-escalation study using a maximal simultaneous intraprostatic boost with RapidArc intensity modulated radiotherapy in intermediate risk prostate cancer	W. James Morris	BC Cancer Agency	2009
fMRI	Studies of Treatment Related Compulsive Behaviours and Impulse Control Disorders in Parkeinson's Disease	Vesna Sossi	Pacific Parkinson's Reasearch Centre	2009
MRI	Imaging Dizziness using 3T MRI	John Phillips	Otology & Neurotology, St. Paul's Hospital	2009
MRI	A Phase 3, Multicenter, Randomized, double Blind, Placebo-Controlled, Parallel Group, Efficacy and Safety Trial of Bapineuzumab (AAB-001, ELN115727) in Subjects with Mild to Moderate AlzheimerÕs disease who are Apolipoprotein E 4 Non-Carriers	Ging-Yuek Robin Hsiung	Neurology	2009
MRI	A Clinical evaluation for the management of patients with major depressive disorder, single or recurrent episode, with deep brain stimulation	Raymond Lam	Psychiatry	2009
MRI	Neuropsychological and neuropathological outcome from concurrent alcohol use and traumatic brain injury: a longitudinal study	Rael Lange	Riverview	2009
MRI	Abdominal shift due to patient position	Tim Salcudean	Electrical Computer Eng	2009
MRI	Sports related knee injury Pilot (SKIP)	Jolanda Cibere	Arthritis Research Centre	2009
MRI	Changes to skeletal muscle structure during contractions	James Wakeling	Biomedical Physiology and Kinesiology SFU	2009
MRI	Anatomical and diffusion imaging of the human arm	Dinesh Pai	Computer Science	2008
MRI	The Effect of PerthesÕ Disease on Hip Cartilage	Kishore Mulpuri	Paediatric Orthopaedics	2008
fMRI	Brain systems involved in belief formation and re-evaluation	Todd Woodward	Psychiatry	2008
MRS	A Randomised, Double-Blind, Placebo-Controlled, Dose-Ranging Safety and Efficacy Study of Oral ELND005(AZD-103) in AlzheimerÕs Disease	Howard Feldman	Neurology	2008
fMRI	Neuroimaging and Quality of Life of Children with Developmental Coordination Disorder	Lara Boyd	Rehabilitation Sciences	2008
fMRI	An FMRI Investigation of Mindfulness	Kalina Christoff	Psychology	2008
MRI	Cognitive Characterization of Individuals genetically at risk for frontotemporal dementia	Kalina Christoff	Psychology	2008
MRI	PET studies of Dopamine Turnover and release in Biolar disorder Fluorodopa PET Study	Lakshmi Yatham	Psychiatry	2008
MRI	Effects of excitatory and inhibitory transcranial magnetic stimulation on motor sequence learning	Lara Boyd	Rehabilitation Sciences	2008
MRI	Development of motor function assessment technology based on computed myography (CMG)	Dinesh Pai	Computer Science	2008
MRI	Visualization and Real-Time Dosimetry for Prostate Brachytherapy	Tim Salcudean	Electrical Computer Eng	2008
MRI	AIM-HIGH Carotid Study	Alex MacKay	Physics and Astronomy	2008
MRI	Pseudoatrophy of the Brain	Tony Traboulsee	Neurology	2008
fMRI	the Ultimatum Game	Elton Ngan	Psychiatry	2008
MRI	Hotel: Co-occurring psychosis, addiction and viral infection	Bill Honer	Psychiatry	2008
MRI	Investigation of intervertebral disc height in REM nd nonREM sleep	Jerome Fryer		2008
MRI	Spatial and Temporal Aspects of Force Production in ParkinsonÕs Disease: Functional Magnetic Resonance Imaging Study - SWI sequence study	Alex Rauscher	UBC MRI Research Centre	2008
fMRI	Waking Salivary Cortisol and DHEA and Serum BDNF Levels in Mood Disorders (the fMRI component)	Allan Young/Mario Liotti	Mood disorders Centre	2008
MRS	Serono - Atacicept Protocol 28156	Peter Reickmann	MS Clinical Resarch	2008
	Centocor Study - a phase 2 double blind, placebo-controlled randomized, dose-ranging study of multiple subcutaneous injections of human monoclonal antibody to 1L-12P40 in subjects with relapsing-remitting multiple sclerosis	Tony Traboulsee		2008
fMRI	Neuroplasticity following sensory therapy in spinal cord injury	Jaimie Borisoff	GF Strong Rehab Centre	2008
MRI	Genzyme Study (2 parts)	Tony Traboulsee	Neurology	2008
fMRI	Neural correlates of cognitive and motor object representations	Todd Handy	Psychology	2008
MRI	Morphology and dimensions of small pig sinal cord and canal in vivo	Peter Cripton	Orthopaedic Engineering	2008
fMRI	Brain Activation: from mechanisms to mobility	Janice Eng	Rehab Sciences	2008
fMRI	How Does Excitatory rTMS influence motor cortical activation?	Lara Boyd	Rehab Sciences	2008
MRI	MRI and Mathematics	Linda Siegel/Christian Beaulieu	Biomeidcal Engineering U of A	2008
fMRI	The Effect of Resistance Training on Cognitive Performance, Cortical Plasticity, and Fall Risk in Women Aged 65 to 75 Years Old: A 12-Month Randomized Controlled Trial.	Teresa Ambrose, Todd Handy	Centre for Hip Health	2008
	3T vs 1-5T Comparison for imaging myelin water	Alex MacKay		2004
MRS	N-acetyl-aspartate measures in the thalamus in first episode schizophrenia before and after exposure to atypical antipsychotics during the early phases of treatment	Donna Lang	Radiology	2004
fMRI	fMRI Studies in ParkinsonÕs Disease	Martin McKeown	Neurology	2004
MRI	3T MRI for Functional Neurosurgery	Chris Honey	Neurology	2004
fMRI	Money matters: An fMRI investigation of the differential response patterns to varying levels of financial reward in healthy people, and patients with schizophrenia	Elton Ngan	Psychiatry	2004
fMRI	Hippocampo-Prefrontal Connectivity during Semantic Reactivation and during Source Monitoring	Todd Woodward	Psychiatry	2004
MRS	A Pilot Clinical Trial of Intravenous Infusion of Autologous Hematopoietic Progenitor Cells in Patients With Amyotrophic Lateral Sclerosis (ALS)	Andy Eisen	Neurology	2004
fMRI	Mechanisms of Attention Orienting	Todd Handy	Psychology	2004
MRS	A prospective study of clinical outcome, brain morphology, cognitive and other functional outcomes in patients after a first episode of mania	Lakshmi Yatham	Psychiatry	2004
fMRI	Hippocampo-prefrontal connectivity	Todd Woodward	Psychiatry	2004
fMRI	New sensory tests for the early detection of dyslexia	Debbie Giaschi	Opthamology	2004
fMRI	Low- and high-level motion processing in children with anisometropic or strabismic amblyopia	Debbie Giaschi	Opthamology	2004
MRI	Linking Mechanical Imaging with Direct Measurements of BoneÕs Mechanical Properties.	Heather McKay	Orthopaedic Engineering	2004
MRS	A Multi-Centered, Randomized Double-Blind, Placebo-Controlled, Parallel Study, Assessing the Add-on effect of Minocycline in Relapsing-Remitting Multiple Sclerosis (RR-MS) Subjects Treated with Glatiramer Acetate (GA): TEVA 9014 Study	Tony Traboulsee	Neurology	2004
MRI	Neuromuscular control of the head and neck in multidirectional seated perturbations.	Timothy Inglis	Human Kinetics	2004
MRI	A biomechanical study of the Dynesys system for flexible posterior stabilization of the lumbar spine: Investigation of facet joint contact under flexion and extension loads using imaging	Tom Oxland	Orthopaedic Engineering	2004
fMRI	The cortical networks of real world memory retrieval	Todd Handy	Psychology	2004
fMRI	Retinoptic Selection as a Factor in Cortical Processing	Todd Handy	Psychology	2004
MRI	A randomized Controlled Trial of a Prevention Strategy for Severe Knee Injury in Youth Soccer.	John Esdaile	Rheumatology	2004
MRI	Three dimensional alignment and early cartilage degeneration in femoroacetabular impingement syndrome	David Wilson	Orthopaedic Engineering	2004
fMRI	Brain Mechanisms Underlying Human Motion Perception	Debbie Giaschi	Opthamology	2004
fMRI	Functional Neuroimaging of Negative Effect in Elite Swimmers	Elton Ngan	Psychology	2004
fMRI	Disease markers and predictors of clinical relapse in Remitted Unipolar Depression: An fMRI study	Raymond Lam	Psychiatry	2004
MRI	Quantitative Assessment of the Functional Adaption of Bone and Cartilage at the Glenohumeral Joint of Manual Wheelchair Users	David Wilson	Orthopaedic Engineering	2004
MRI	Nondestructive characterization and modelling of bacterial wood	Sencer Alkan	Forintek Canada Corp	2004
MRI	3D Modelling of the Human Vocal Tract Ð Initial Investigation	Sydney Fels	Electrical Computer Eng	2004
fMRI	Spontaneous forms of thought: an fMRI investigation	Kalina Christoff	Psychology	2004
MRS	A Double-Blind, Placebo-Controlled Multicentre Study to Evaluate the Efficacy and Safety of MBP8298 in Subjects with Secondary Progressive Multiple Sclerosis.	Tony Traboulsee	Neurology	2004
fMRI	Abstract versus concrete thought during anagram completion: an fMRI investigation	Kalina Christoff	Psychology	2004
MRI	Alzheimer Disease Neuroimaging Initiative	Howard Feldman	Neurology	2004
fMRI	A Functional MRI Study of Face Perception in normal subjects, prosopagnosic patients, and patients with Cerebral Infarcts.	Jason Barton	Opthamology	2004
MRS	The UBC HuntingtonÕs Disease NMR Spectroscopy Study	Blair Levitt	Neurology	2004
MRI	Three-dimensional measurement of knee kinematics in vivo: applications to knee pain and osteoarthritis Ð ex vivo cadaver studies	David Wilson	Orthopaedic Engineering	2004
fMRI	Spatial and Temporal Aspects of Force Production in ParkinsonÕs Disease: Functional Magnetic Resonance Imaging Study	Martin McKeown	Neurology	2004
fMRI	Functional Neuroimaging of the Hippocampo-Prefrontal Neural System across the Spectrum of Schizophrenia	Todd Woodward	Psychiatry	2004
fMRI	Functional Neuroimaging of the Effects of Template Complexity in Visual Search	Vince Di Lollo	Psychiatry	2004
MRI	DW and DCE MRI in prostate cancer diagnosis - a volunteer study	Piotr Kozlowski	Radiology	2004
MRS	A Double-Blind, Placebo-Controlled Multicentre Study to Evaluate the Efficacy and Safety of MBP8298 in Subjects with Secondary Progressive Multiple Sclerosis.	Tony Traboulsee	Neurology	2004
fMRI	Somatotopy of Speech Motor Cortex	Elton Ngan	Psychiatry	2004
fMRI	A combined fMRI/DTI analysis of the cerebral motion pathways.	Jason Barton	Opthamology	2004
MRI	Neuropsychological and neuropathological effects of acute vs chronic alcohol consumption: Outcome from traumatic brain injury	Rael Lange	Riverview	2004
MRI	Evaluation of delayed gadolinium enhanced magnetic resonance imaging (dGEMRIC) as a more sensitive measure of intervertebral disc degeneration.	David Wilson	Orthopaedic Engineering	2004
fMRI	Using real-time fMRI feedback in patients with recurrent unipolar depression	Kalina Christoff	Psychology	2004
fMRI	Working memory representations at different levels of abstraction: an fMRI investigation	Kalina Christoff	Psychology	2004
fMRI	Attention in a Dynamic World: Influences of the Optic Flow Field on Visuospatial Attention	Todd Handy	Psychology	2004
fMRI	The Neural Basis of Vocal Imitation	Steven Brown	SFU	2004
fMRI	Low-level and High-level Motion Processing in Amblyopic Children	Deborah Giaschi	Opthamology	2004
fMRI	Functional Neuroimaging of the Frontal Lobe during Cognitive Flexibility Tasks	Elton Ngan, Todd Woodward	Riverview	2004
MRI	Effects of hydration status on magnetic resonance imaging measurements of brain volume and water content.	Tony Traboulsee	Neurology	2004
MRI	New Imaging and Diagnostic Modalities: A Novel Quantitative Magnetic Resonance Imaging Technique for the Assessment of Cervical Spondylotic Myelopathy	Armin Curt	Neurology	2004
fMRI	Mapping networks subserving sequential and associative decision making processes	Elton Ngan	Psychiatry	2004
fMRI	Working memory representations at different levels of abstraction: an fMRI investigation	Kalina Christoff	Psychology	2004
fMRI	Compensatory Brain Activation after Stroke	Lara Boyd	Rehabilitation Sciences	2004
fMRI	Force Production in individuals with stroke or spinal cord injury using functional magnetic resonance imaging	Janice Eng	Rehabilitation Sciences	2004
fMRI	The Effect of Resistance Training on Cognitive Performance, Cortical Plasticity, and Fall Risk in Women Aged 65 to 75 Yead Old: A 12-Month Randomized Controlled Trial	Teresa Ambrose, Todd Handy	Rehabilitation Sciences	2004
fMRI	Investigating prefrontal cortex functions using real-time fMRI	Kalina Christoff	Psychology	2004
fMRI	An fMRI Investigation of Rest	Kalina Christoff	Psychology	2004
fMRI	The neural basis of deductive reasoning errors in schizophrenia	Elton Ngan	Psychiatry	2004
fMRI	Topographical Disorientation in Brain Damaged Patients.	Jason Barton	Opthamology	2004
MRI	Sequence Development for Musculoskeletal Applications in the Knee and Hip	David Wilson	Orthopaedic Engineering	2004
MRI	Effect of acetabular labral tears, repair and resection on hip cartilage loading: A 7T MR study	David Wilson	Orthopaedic Engineering	2004
MRI	Monitoring stereotactic radiotherapy treatment of acoustic neuromas	Stefan Reinsberg	Physics and Astronomy	2004
MRI	Axial Strain Estimation in Tissue Phantoms	Dinesh Pai	Computer Science	2004
MRI	The effect of infection following ACL reconstruction on cartilage health	David Wilson	Orthopaedic Engineering	2004
MRI	Dividing the undivided: Cardiac dynamics of leatherback and green turtles	David Jones	Zoology	2004
MRI	Impaction allografting - MR imaging for the bone cement morphology in a cadaveric femur model	Tom Oxland	Orthopaedic Engineering	2004
fMRI	Multi-Site Pediatric Network for fMRI Mapping in Childhood Epilepsy	Bruce Bjornson	Neurology	2004
MRI	Characterising Myelination in Multiple Sclerosis	Alex MacKay	Radiology	2004
MRI	In vivo electrophysiological evaluation of DTI depiction of the deep seated principle motor pathways in human brain. A clinical 3T mRI and functional sterotaxy study	Chris Honey	Neurology	2004
fMRI	Neurological Changes with Motor Learning	Nicola Hodges	Human Kinetics	2004
MRI	Early Hip Osteoarthritis MRI Pilot: dGEMRIC Substudy	Jolanda Cibere	Rheumatology	2004
MRI	Protocol Development for Diffusion Tensor Imaging of the Human Forearm	Dinesh Pai	Computer Science	2004
MRI	Neuropsychological and neuropathological effects of acute versus chronic alcohol consumption on outcome of traumatic brain injury	Rael Lange	Riverview	2004
fMRI	The cortical basis of motion perception deficits in amblyopia	Debbie Giaschi	Opthamology	2004
MRI	TRACK-HD	Blair Levitt	Neurology	2004
fMRI	The cortical basis of reading and temporal processing deficits in dyslexia	Debbie Giaschi	Opthamology	2004
fMRI	Does cortical stimulation facilitate motor learning after stroke?	Lara Boyd	Rehabilitation Sciences	2004
MRI		Alasdair Barr	Psychiatry	2004
fMRI	The Neuronal Basis of Developmental Stuttering	Mario Liotti	SFU Psychology	2004
fMRI	An NMR Investigation of Pedophilia	Kalina Christoff	Psychology	2004
MRI	Dynamic 3D upper airway modeling of the effect of oral appliances for the treatment of obstructive sleep apnea/hypopnea	John Fleetham	Respiratory Medicine	2004
fMRI	Recovery after stroke: what is the role of the undamaged, contralesional cortex?	Lara Boyd	Rehabilitation Sciences	2004
MRI	Which white matter tracts are involved in distinct psychiatric and surgically treated disorders ?	Chris Honey	Neurology	2004
fMRI	The neural basis of deductive reasoning errors in schizophrenia: Conflict and emotion	Elton Ngan	Psychiatry	2004
fMRI	Integration of disconfirmatory evidence in pychosis: Cognitive and Neural findings	Todd Woodward	Psychiatry	2004